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2C General skeletal

The general structure of a 2C compound.

2C refers to the family of synthetic phenethylamines that contain methoxy groups on the 2 and 5 positions of the benzene ring. The majority of these compounds were initially synthesized by the American pharmacologist Alexander Shulgin in the 1970's and 80's, who coined the acronym 2C in reference to the two carbon atoms in between the benzene ring and the amino group. Most (or all) of the compounds act as partial agonists on the 5-HT2A receptor and as a result they are all potent psychedelic drugs.

List of 2C compounds[]

  • 2C-B
  • 2C-C
  • 2C-D
  • 2C-E
  • 2C-F
  • 2C-G
  • 2C-G-3
  • 2C-G-4
  • 2C-G-N
  • 2C-H
  • 2C-I
  • 2C-N
  • 2C-O
  • 2C-O-4
  • 2C-P
  • 2C-SE
  • 2C-T
  • 2C-T-2
  • 2C-T-4
  • 2C-T-7
  • 2C-T-8
  • 2C-T-9
  • 2C-T-13
  • 2C-T-15
  • 2C-T-17
  • 2C-T-21
  • 2C-TFM