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Chemical compound
Dopamine
Dopamine-2D-skeletal
Dopamine-3D
Nomenclature & Identifiers
Systematic name 4-(2-aminoethyl)benzene-1,2-diol
Other names 2-(3,4-dihydroxyphenyl)ethylamine;

3,4-dihydroxyphenethylamine; 3-hydroxytyramine; DA; Intropin;
Revivan; Oxytyramine

ChemSpider ID 661
PubChem ID 681
Properties
Formula C8H11NO2
Molar mass 153.18 g mol-1
Melting point 128 °C (401 K)
Solubility 60.0 g 100ml-1 (water)
Hazards
Related compounds


Dopamine is a phenethylamine alkaloid that acts as a neurotransmitter in humans and is classified as one of the catecholamines.

Biosynthesis[]

Dopamine is synthesised in the body from the amino acid L-tyrosine.[1] Tyrosine, sourced from proteins in the diet, is first hydroxylated to L-DOPA by the enzyme tyrosine hydroxylase, which is then decarboxylated to dopamine by the enzyme aromatic L-amino acid decarboxylase. Within neurons, dopamine is packaged into vesicles which are released into the synapse in response to a presynaptic action potential.

References[]

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